Pope Leo heads off for 12-day tour of South America weeks after lung cancer surgery

The pontiff will hold meetings and celebrate Mass in Uruguay, Argentina and Peru, with the latter attracting particular interest. The trip will be the longest and farthest of his papacy so far.

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Pope Leo XIV waves as he boards his plane heading to Montevideo for a 12 days visit to Uruguay, Argentina and Peru, at Rome's Fiumicino airport on November 6, 2026
The pope took off from Rome’s Fiumicino airport in the early hours of the morningImage: Filippo Monteforte/AFP

The plane carrying Pope Leo XIV to South America for the beginning of his almost two-week tour set off from Rome on Friday.

Following a 13-and-a-half-hour flight, the pontiff is set to land in Uruguay, where he will spend three days before heading on to Argentina, and finally Peru.

The 71-year-old US-born pope is recovering from a lung cancer surgery that took place just three weeks ago.

Latin America is home to around 40% of the world’s 1.4 billion Catholics, for whom the pope is their spiritual leader. However, fewer and fewer people on the continent identify as Catholic.

What is Pope Leo planning for his visit to Uruguay?

Pope Leo’s first leg of the tour takes him to Uruguay, the most secular Latin American country.

It was the first country in the world to legalize recreational marijuana use and has since legalized abortion, same-sex marriage and assisted dying, all against opposition from the Catholic Church.

However, the enthusiasm around Leo’s visit has come as a bit of a surprise, with tickets for his prayer vigil at Montevideo’s Centenario Stadium selling out in just two days.

A person in a crowd holding up a small banner that reads 'Uruguay celebrates your arrival' in Spanish with a picture of Pope Leo, in Montevideo on October 31, 2026
The pope is expected to express opposition to some of the more liberal policies enacted in UruguayImage: Lucas Aguayo Araos/Anadolu/picture alliance

The trip will begin with a meeting with President Yamandu Orsi, leader of a center-left alliance. He is also planning to visit the Casavalle neighborhood, which is notorious for its high rates of poverty and violence.

With the first papal visit to Uruguay since 1988, Leo will be hoping to reinvigorate the faith in a country where only a fraction of believers attend Mass.

What will Pope Leo do in Argentina?

On Sunday, Leo will cross over to neighboring Argentina, the home of his papal predecessor Francis, who, however, disappointed his native compatriots by never returning home as pope.

At the beginning of Francis’s papacy, some 71% of Argentinians identified as Catholic, according to the Pew Research Center. By 2024, this had fallen to 58%.

A drone view shows a mural depicting Pope Leo, before his trip to Argentina from November 8 to 11, in Claypole, on the outskirts of Buenos Aires, Argentina, November 4, 2026
Leo will hope his visit makes up for the refusal by his predecessor to visit his home countryImage: Agustin Marcarian/REUTERS

Leo is set to meet with Argentinian President Javier Milei, who has come under criticism from the Catholic Church for his sweeping cuts that have hampered programs for the poor and needy.

He is also planning to meet with business leaders, trade unions, workers and social representatives.

Pope Leo to return to Peru

The final leg of the trip, on Wednesday, will see Leo return to Peru, where he lived and preached for two decades.

There is excitement about his visit to Peru, with the pope planning to celebrate Mass in his old diocese of Chiclayo as well as in the mountain village of Santa Cruz de Succhabamba.

The pope will also celebrate Mass in the former Incan capital city of Cusco before honoring Peru’s indigenous population by traveling to Pucallpa in the Peruvian Amazon.

The excitement can be seen in the street vendors selling T-shirts and rosaries with his likeness, while bakeries have been selling Leo bread.

Peru has also seen a weakening of the faithful in recent years, with the Catholic population falling from 76% in 2013-2014 to around 67% now.

A Pope Leo XIV cookie is displayed in a store in Chiclayo, Peru, Thursday, November 5, 2026
Peruvian Catholics have shown particular interest in the pope’s visit as a type of homecomingImage: Martin Mejia/AP Photo/picture alliance

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